Skin Immunology and Rejection in VCA and Organ Transplantation

The changing immunology of organ transplantation.

The engrafted organ becomes a chimera as the recipient's leukocytes station themselves in the transplant. Remarkably, the recipient becomes chimeric as well, in a reverse migration involving immune cells from the graft. Interactions between donor and recipient cells are tolerogenic--a process with implications for the goal of graft acceptance with minimal immunosuppression.

Review of the Early Diagnoses and Assessment of Rejection in Vascularized Composite Allotransplantation

The emerging field of vascular composite allotransplantation (VCA) has become a clinical reality. Building upon cutting edge understandings of transplant surgery and immunology, complex grafts such as hands and faces can now be transplanted with success. Many of the challenges that have historically been limiting factors in transplantation, such as rejection and the morbidity of immunosuppressi...

cytomegalovirus and acute rejection in kidney transplantation

Skin cancer after solid organ transplantation.

Sir, We read the article by Belloni-Fortina et al. (1) with great interest. This retrospective study focused on the incidence of, and risk factors for, skin complications among liver transplant patients. They concluded that in these recipients the risk of premalignant and malignant skin lesions was lower than that of other solid organ transplants. Although organ transplant recipients are predis...

immunology of hcv and hbv in renal failure and transplantation